Prescription drugs that inhibit CYP2D6 action, for example paroxetine and quinidine, may trigger decreased clearance of oxycodone which may lead to a rise in oxycodone plasma concentrations. Concurrent administration of quinidine resulted in a rise in oxycodone Cmax by 11%, AUC by 13%, and t½ elim.Ask your health care provider or pharmacist if you

Like all comprehensive opioid agonists, there's no ceiling effect for analgesia with oxycodone. Clinically, dosage is titrated to offer satisfactory analgesia and will be restricted by adverse reactions, such as respiratory and CNS despair.My boyfriend took his possess everyday living, so I was in a really undesirable position and residing away fro